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Dermatology NEJ Cases Patient with Decreased Skin Turgor

Patient with Decreased Skin Turgor

A 61-year-old man with a vasoactive intestinal polypeptide-secreting neuroendocrine tumor (VIPoma) and diarrheal fluid losses exceeding 10 liters per day was transferred to the intensive care unit with severe volume depletion. On physical examination, the blood pressure was 54/30 mm Hg, and there was sinus tachycardia of 156 beats per minute. His total enteric fluid loss was 17 liters in the first 2 days after admission. image The patient was also noted to have severely decreased skin turgo

 

Discus reason for Decreased Skin Turgor ?

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